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Pass the American Society of Microbiology ASM-ABMM ABMM Questions and answers with ExamsMirror

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Questions # 1:

For epidemiological tracking and outbreak investigations of Clostridioides difficile infection (CDI), which molecular typing method based on PCR amplification targeting repetitive elements within the pathogenicity locus (PaLoc) has historically been widely used and designated by specific nomenclature (e.g., NAP1/BI/027)?

Options:

A.

Multilocus sequence typing (MLST)

B.

Pulsed-field gel electrophoresis (PFGE)

C.

PCR Ribotyping

D.

Whole-genome sequencing (WGS) SNP analysis

Questions # 2:

Which of the following viruses is an enveloped, double-stranded DNA virus known to cause latent infections often reactivated during immunosuppression?

Options:

A.

Influenza A virus

B.

Rotavirus

C.

Cytomegalovirus (CMV)

D.

Poliovirus

Questions # 3:

A patient with AIDS develops a disseminated fungal infection. Blood cultures grow a yeast that produces pseudohyphae and terminal chlamydospores on cornmeal agar. The patient's CD4+ T-cell count is below 50 cells/µL. The MOST likely causative organism is:

Options:

A.

Aspergillus fumigatus

B.

Cryptococcus neoformans

C.

Candida albicans

D.

Pneumocystis jirovecii

Questions # 4:

A patient with a history of valvular heart disease undergoes a dental procedure and subsequently develops a bloodstream infection with Streptococcus mutans. This organism gains access to the bloodstream primarily due to:

Options:

A.

Active invasion of the oral mucosa.

B.

Transient bacteremia resulting from the procedure.

C.

Formation of a protective biofilm on the teeth.

D.

Production of potent extracellular enzymes.

Questions # 5:

A patient develops a severe gastrointestinal illness after consuming undercooked poultry. Stool culture yields a Gram-negative, microaerophilic, curved bacillus that is oxidase-positive. The MOST likely organism is:

Options:

A.

Salmonella enterica

B.

Shigella dysenteriae

C.

Campylobacter jejuni

D.

Yersinia enterocolitica

Questions # 6:

A clinical microbiology laboratory is performing antimicrobial susceptibility testing on a Klebsiella pneumoniae isolate. The isolate is resistant to multiple beta-lactam antibiotics, and further testing reveals the presence of a carbapenemase enzyme. The MOST clinically significant carbapenemase in Klebsiella pneumoniae is often:

Options:

A.

AmpC beta-lactamase

B.

Extended-spectrum beta-lactamase (ESBL)

C.

Klebsiella pneumoniae carbapenemase (KPC)

D.

Metallo-beta-lactamase (MBL)

Questions # 7:

A clinical microbiology laboratory is implementing a new laboratory information system (LIS). A critical step in the validation process is ensuring the accurate and reliable transfer of data, including patient demographics, test orders, and results. This aspect of validation primarily focuses on:

Options:

A.

Analytical sensitivity and specificity.

B.

Clinical sensitivity and specificity.

C.

Data integrity and interoperability.

D.

Workflow efficiency and user training.

Questions # 8:

A patient with a history of travel to Southeast Asia presents with fever, severe headache, and altered mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein, but routine bacterial and viral cultures are negative. Serological testing of CSF is positive for IgM antibodies against Japanese encephalitis virus. The MOST likely mode of transmission for this infection is:

Options:

A.

Ingestion of contaminated food or water.

B.

Respiratory droplets from an infected individual.

C.

Bite of an infected mosquito.

D.

Direct contact with infected animals.

Questions # 9:

A patient develops a severe skin and soft tissue infection following a boating accident in the Gulf Coast. Wound cultures grow a Gram-negative, halophilic bacterium that is oxidase-positive. The MOST likely organism is:

Options:

A.

Aeromonas hydrophila

B.

Vibrio vulnificus

C.

Pseudomonas aeruginosa

D.

Shewanella putrefaciens

Questions # 10:

A public health investigation is underway following several cases of encephalitis in a specific geographic region during the summer months. Mosquitoes are abundant in the area. Serological testing of patient CSF samples reveals IgM antibodies against a flavivirus. The MOST likely causative agent is:

Options:

A.

Rabies virus

B.

West Nile virus

C.

Jamestown Canyon virus

D.

Eastern equine encephalitis virus

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