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Pass the American Society of Microbiology ASM-ABMM ABMM Questions and answers with ExamsMirror

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Questions # 11:

A clinical microbiology laboratory is performing antimicrobial susceptibility testing on a Streptococcus pneumoniae isolate using broth microdilution. The lowest concentration of antibiotic that inhibits visible growth of the organism is reported as the:

Options:

A.

Zone diameter

B.

Minimum inhibitory concentration (MIC)

C.

Minimum bactericidal concentration (MBC)

D.

Breakpoint

Questions # 12:

A patient with a history of solid organ transplantation develops diarrhea and abdominal cramps. Stool studies are negative for bacterial pathogens and C. difficile toxins. Colonoscopy reveals characteristic cytomegalic inclusion bodies in colonic biopsies. The MOST likely causative agent is:

Options:

A.

Adenovirus

B.

Norovirus

C.

Cytomegalovirus (CMV)

D.

Rotavirus

Questions # 13:

A sputum sample from a patient with suspected pulmonary tuberculosis is submitted for AFB smear and culture. The smear is reported as positive for acid-fast bacilli (4+). Which method is considered the gold standard for confirming the identification of Mycobacterium tuberculosis complex from culture?

Options:

A.

Growth rate and colony morphology on Löwenstein-Jensen media

B.

Niacin accumulation test

C.

Nucleic acid amplification test (NAAT) targeting specific MTC sequences

D.

HPLC analysis of mycolic acids

Questions # 14:

A patient presents with symptoms suggestive of primary syphilis. Which diagnostic test typically becomes positive earliest in the course of infection?

Options:

A.

Rapid Plasma Reagin (RPR)

B.

Venereal Disease Research Laboratory (VDRL) test on CSF

C.

Darkfield microscopy of lesion exudate

D.

Treponema pallidum particle agglutination (TP-PA)

Questions # 15:

A microbiology laboratory receives a bronchoalveolar lavage sample from a patient with suspected ventilator-associated pneumonia. Quantitative culture yields >10^5 CFU/mL of a Gram-negative rod. Identification reveals Stenotrophomonas maltophilia. The MOST significant resistance mechanism commonly associated with this organism is:

Options:

A.

Production of extended-spectrum beta-lactamases (ESBLs).

B.

Intrinsic resistance mediated by efflux pumps and specific enzymes.

C.

Target site modification in DNA gyrase.

D.

Ribosomal methylation leading to macrolide resistance.

Questions # 16:

During an investigation of a foodborne outbreak linked to a church supper, 80 people ate the suspected chicken dish, and 32 subsequently developed gastroenteritis. Among 50 people who did not eat the chicken dish, 5 developed similar symptoms. What is the attack rate among those who ate the chicken dish?

Options:

A.

5%

B.

10%

C.

40%

D.

64%

Questions # 17:

A patient develops a vesicular rash on their hands and feet, accompanied by fever and oral ulcers. The MOST likely causative agent is:

Options:

A.

Varicella-zoster virus

B.

Herpes simplex virus

C.

Coxsackievirus A

D.

Measles virus

Questions # 18:

During an outbreak of norovirus gastroenteritis in a nursing home, environmental swabs are collected to identify the source of the infection. Which of the following methods would be MOST appropriate for detecting norovirus in these samples?

Options:

A.

Culture on human embryonic kidney (HEK) cells

B.

Gram staining and microscopy

C.

Reverse transcription-polymerase chain reaction (RT-PCR)

D.

Enzyme-linked immunosorbent assay (ELISA) for viral antigens

Questions # 19:

Under the Clinical Laboratory Improvement Amendments (CLIA), participation in an approved external Proficiency Testing (PT) program serves primarily to:

Options:

A.

Fulfill requirements for laboratory accreditation by The Joint Commission only.

B.

Provide an objective, ongoing assessment of the accuracy and reliability of the laboratory's testing compared to its peers.

C.

Validate the performance characteristics (e.g., sensitivity, specificity) of newly implemented test methods.

D.

Determine the reference intervals (normal ranges) for quantitative assays performed by the laboratory.

Questions # 20:

A patient with HIV infection and a very low CD4+ T-cell count develops a disseminated infection with a fungus that is commonly found in pigeon droppings. The MOST likely causative agent is:

Options:

A.

Candida glabrata

B.

Cryptococcus gattii

C.

Cryptococcus neoformans

D.

Saccharomyces cerevisiae

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